Классификация USP L ВЭЖХ колонок Agilent Technologies

The US Pharmacopeia (USP) is a standard source for many pharmaceutical methods. The USP specifies
columns by packing materials rather than by manufacturer. The USP has updated its L1 definitions, listed
below you will see the most recent definitions and columns that apply. Rapid Resolution High Throughput
(RRHT) columns are now choices in the L1, L7, and L11 categories.

 

 

USP Column
L1 Octadecyl silane chemically bonded to porous silica or ceramic microparticles,
1.5 to 10 µm in diameter, or a monolithic rod
Poroshell 120 EC-C18
Poroshell 120 SB-C18
Poroshell 300SB-C18
Poroshell 300 Extend-C18
ZORBAX Eclipse Plus C18
ZORBAX Eclipse XDB-C18
ZORBAX StableBond SB-C18
ZORBAX Rx-C18ZORBAX Extend-C18
ZORBAX ODS
ZORBAX ODS classic
Pursuit XRs C18
Pursuit C18
Pursuit C18-A
Polaris C18-Ether
SepTech ST60 C18
SepTech ST150 C18
Agilent Prep C18
L3 Porous silica particles, 1.5 to 10 µm in diameter, or a monolithic silica rod ZORBAX HILIC Plus
ZORBAX SIL
ZORBAX Rx-SIL
Pursuit XRs Si
Polaris Si-A
Agilent Prep
L7 Octylsilane chemically bonded to totally porous silica particles,
1.5 to 10 µm in diameter,
or a monolithic silica rod
Poroshell 120 EC-C8
Poroshell 120 SB-C8
Poroshell 300SB-C8
ZORBAX Eclipse Plus C8
ZORBAX Eclipse XDB-C8
ZORBAX SB-C8
ZORBAX Rx-C8
ZORBAX C8
Pursuit XRs C8
Pursuit C8
Polaris C8-A
Polaris C8-Ether
L8 An essentially monomolecular layer of aminopropylsilane chemically bonded
to totally porous silica gel support, 3 to 10 µm in diameter
ZORBAX NH2
Polaris NH2
L9 Irregular or spherical, totally porous silica gel having a chemically bonded,
strongly acidic cation-exchange coating, 3 to 10 µm in diameter
ZORBAX SCX
L10 Nitrile groups chemically bonded to porous silica particles, 3 to 10 µm in diameter ZORBAX CN
ZORBAX SB-CN
ZORBAX Eclipse XDB-CN
L11 Phenyl groups chemically bonded to porous silica particles, 1.5 to 10 µm in diameter ZORBAX Eclipse XDB Phenyl
ZORBAX Eclipse Plus Phenyl-Hexyl
ZORBAX Phenyl
Poroshell 120 Phenyl-Hexyl
Pursuit XRs DiPhenyl
Pursuit DiPhenyl
L13 Trimethylsilane chemically bonded to porous silica particles, 3 to 10 µm in diameter ZORBAX TMS
L14 Silica gel having a chemically bonded, strongly basic quaternary ammonium
anion-exchange coating, 5 to 10 µm in diameter
ZORBAX SAX
IonoSpher A
L17 Strong cation-exchange resin consisting of sulfonated cross-linked
styrene-divinylbenzene copolymer in the hydrogen form, 7 to 11 μm
in diameter
Hi-Plex H
L19 Strong cation-exchange resin consisting of sulfonated cross-linked
styrene-divinylbenzene copolymer in the calcium form, 9 μm in diameter
Hi-Plex Ca
Hi-Plex Ca (Duo)
L20 Dihydroxypropane groups chemically bonded to porous
silica particles, 3 to 10 μm in diameter
LiChrospher Diol
L21  A rigid spherical styrenedivinylbenzene copolymer, 5 to 10 µm in diameter PLRP-S
Plgel
L22 A cation-exchange resin made of porous polystyrene
gel with sulfonic acid groups, about 10 µm in size
Hi-Plex H
L25 Packing having the capacity to separate compounds with a MW
range from 1,000 to 5,000 da (as determined by the polyethylene oxide),
applied to neutral, anionic and cationic water-soluble polymers.
A polymethacrylate resin base, crosslinked with polyhydroxylated ether
(surface contained some residual carboxyl functional gruops) was found suitable
PL aquagel-OH
L33 Packing having the capacity to separate dextrons by molecular size
over a range of 4,000 to 500,000 da.
It is spherical, silica-based, and processed to provide pH stability
ZORBAX GF-250
Bio SEC-3
Bio SEC-5
ProSEC
L34 Strong cation-exchange resin consisting of sulfonated cross-linked
styrene-divinylbenzene copolymer in the lead form, about 9 µm in diameter
Hi-Plex Pb
L35 A zirconium-stabilized spherical silica packing with a hydrophilic (diol- type)
molecular monolayer bonded phase having a pore size of 150Å
ZORBAX GF-250
ZORBAX GF-450
L43  Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer,
5 to 10 µm in diameter
Pursuit PFP
L45  Beta cyclodextrin bonded to porous silica particles, 5 to 10 µm in diameter ChiraDex Chiral
L50 Multifunction resin with reversed-phase retention and strong anion- exhange functionalities.
The resin consists of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer,
3 to 15 µm in diameter, and a surface area of not less than 350 m2 per g.
Substrate is coated with quarternary ammonium functionalized latex particles
consisting of styrene cross-linked with divinylbenzene
ZORBAX 300SCX
L52 Weak cation-exchange resin made of porous silica with sulfopropyl groups,
5 to 10 µm in diameter
IonoSpher C
L53 Weak cation-exchange resin consisting of ethylvinylbenzene, 55% crosslinked with
divinylbenzene copolymer, 3 to 15 µm diameter. Substrate is surface grafted with
carboxylic acid and/or phosphoric acid functionalized monomers.
Capacity not less than 400 µEq/column
Bio SAX
L56 Propyl silane chemically bonded to totally porous silica particles, 3 to 10   ZORBAX SB-C3
L57 A chiral-recognition protein, ovomucoid, chemically bonded to silica particles,
about 5 µm in diameter, with a pore size of 120Å
Ultron ES-OVM
L58 Strong cation-exchange resin consisting of sulfonated cross-linked
styrene-divinylbenzene copolymer in the sodium form,
about 6 to 30 µm in diameter
Hi-Plex Na
Hi-Plex Na (Octo)
L60 Spherical, porous silica gel, 10 µm in diameter, the surface has been covalently
modified with alkyl amide groups and endcapped
ZORBAX Bonus-RP
Poroshell 120 Bonus-RP
Polaris Amide-C18

 

 


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